Gene synthesis has transformed the way researchers design and engineer DNA. What once required multiple rounds of site-directed mutagenesis can now be achieved through de novo synthesis of virtually any double-stranded DNA sequence, delivered accurately and on schedule.

Receive custom synthetic genes in just 15 working days and gain a head start on your project timelines. Optimise gene expression, eliminate unwanted sequence motifs, and reduce challenges associated with secondary structures through expertly designed DNA constructs.

Focus on advancing your research while we identify and deliver the right clone for your application.

Choose your gene

Depending on the length and complexity of a gene or project, we offer different categories of synthetic genes.

Standard genes

Standard genes are defined by the following criteria

  • Moderate guanine-cytosine (GC) content (40–65%)
  • No extensive repeats (>20bp) or critical hairpin structures
  • No extensive homopolymer stretches (>20bp)

Complex genes

If any of the following descriptions below match your request, our service category complex genes would be most suitable for you

  • Consultation included
  • Extreme GC content (very high or low)
  • Long repeats or secondary structures are part of the gene

Gene strands

Gene strands are a cost-efficient alternative to short genes with no complexities

  • Delivery time: 15 working days
  • Gene strand lengths: 20-99 bp
  • Delivered as linear, double-stranded DNA fragments

Applications

Synthetic genes: the universal key in molecular biology

Expression improvement in heterologous systems

  • Codon usage adaptation
  • Promoter and enhancer elements

Cloning applications

  • Subcloning
  • cDNA cloning
  • qPCR and PCR standards

Optimisation of constructs

  • Introduction/removal of good and bad motifs
  • Construction of hybrid genes
  • Screening for improved properties of proteins

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