Acquired or sporadic cancers develop due to lifestyle and environmental factors. Genetic damage is driven by a combination of factors, including:

• Environmental and occupational exposure to carcinogens: Common examples of external factors that physically damage DNA include ultraviolet (UV) radiation from the sun, certain viruses (like HPV), and hazardous chemicals such as asbestos, benzene, and organophosphate insecticides. The EU classify carcinogens into category 1A, 1B, and 2, which are regulated according to the severity of the risk they pose.
• Lifestyle choices: Tobacco smoke, alcohol, obesity, excess body weight, certain drugs & drug-use.
• Ageing: The longer we live, the more time we have to accumulate random genetic errors due to impaired DNA repair enzymes, mitochondrial mutations, shortening telomeres, and cellular senescence.

DNA panels - 64 genes

DNA is extracted from biological tissue and preserved using Formalin-Fixed Paraffin-Embedded tissue (FFPE) method. Specific regions of DNA are then isolated using a molecular biology technique known as hybrid capture before genetic sequencing.

Gene List (Updated May 2026):

RNA panels - 66 genes

RNA extraction follows the same workflow but we first convert it into complementary DNA (cDNA) using a technique called Reverse Transcription. Reverse Transcriptase reads the extracted RNA and builds a complementary DNA (cDNA) strand.

Gene List (Updated May 2026):

Our areas of expertise

Gynecological tumours 

1. Breast
2. Endometrial + microsatellite instability (MSI) status.
3. Ovarian panel + homologous recombination deficiency (HRD). 

20% to 30% of cases exhibit high microsatellite instability (MSI-H) or a mismatch repair deficiency (dMMR). MSI-H tumors are highly responsive to immunotherapy and indicate a significantly increased risk for Lynch syndrome

HRD-positive status helps doctors select targeted therapies like PARP inhibitors, which are highly effective for approximately 50% of advanced ovarian

Digestive tumours

Colorectal + MSI, pancreatic & cholangiocarcinoma

Central nervous system tumours 

Pan cerebral, glioma, medulloblastoma

Other Organs

Skin, prostate, thyroid, bone & soft tissue, lung, brain. 

Pre-cancer screen

Pre-cancer screen results support the diagnosis and prognosis of cancer as well as the selection of a suitable targeted therapy, which deliver localised radiation to destroy cancerous and pre-cancerous cells while sparing healthy tissue.