Innovation for pharmaceutical and cosmetic product delivery
By Christelle Gélis, Eurofins ADME Bioanalyses, France
After 11 July 2013, all performance of cosmetics will have to be clearly documented. Due to the cost of development of a new ingredient (REACh: Registration, Evaluation and Authorisation of Chemicals), most of the companies would prefer to use an approved ingredient. Therefore, most of the cosmetic research is directed toward the use of new local delivery devices, for example:
- Different types of patches
- Textile prints with an embedded active ingredient such as caffeine to improve lipolysis
- Pre-treatment of the skin to improve dermal absorption
To validate these different techniques, the availability of the active ingredient at the site of action has to be confirmed. In vitro testing, using human skin mounted on Franz cells, allows for the measurement of the active ingredient present in the different skin layers.
Internal dermal absorption data generated by Eurofins' dedicated team show that these innovative technologies can significantly improve the absorption of active ingredients through human skin. They also demonstrate the importance of testing active ingredients and formulations utilising Franz cell technology.
To discover how Eurofins can meet your pharmaceutical and cosmetic testing challenges, contact: skin@eurofins.com
