Webinar | The Extracellular Matrix: The Forgotten side of Skin Longevity hallmarks

The extracellular matrix (ECM) is a fundamental component of skin structure and function, playing a central role in skin firmness, resilience and visible aging. Beyond collagen alone, the ECM encompasses a complex network of proteins and signaling molecules that collectively influence skin quality, repair capacity and long-term skin health.

While often overlooked in current longevity frameworks, ECM alteration is increasingly emerging as an important hallmark of skin longevity, closely linked to the progressive decline of skin function and appearance over time. As pro-aging and skin longevity claims continue to evolve, brands face a growing challenge: how to scientifically demonstrate significant effects on the ECM, from underlying biological mechanisms to clinically visible outcomes.

In this 30-minute flash webinar, Eurofins Cosmetics & Personal Care experts will present complementary ex vivo and in vivo approaches to assess ECM-related effects, supporting ingredient development, product validation and robust claims substantiation.

Agenda

15:00 – 15:15   Understanding Dermal ECM : Structure, Types and Model Based Evaluation
Giuseppe Percoco / Marie Reynier

An overview of the dermal extracellular matrix (ECM), including its key structural components, such as collagens, elastin and glycosaminoglycans, and their biological roles in maintaining skin integrity, function and resilience over time. This session will highlight ECM alteration as a hallmark of skin aging and longevity, and present relevant ex vivo approaches, including human skin explants, used to investigate mechanisms of action and modulation of ECM-related pathways.

15:15 – 15:25 Measuring Collagen In Vivo: From Direct Imaging to Functional Clinical Readouts
Anne Sirvent

A presentation of direct and indirect in vivo approaches to assess collagen in ECM, including advanced imaging technologies and biophysical methods, translating dermal changes into clinically meaningful evidence.

15:25 – 15:30 Live Q&A

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