Process development teams require reliable data to understand how to optimise and scale up their manufacturing bioprocess. Detailed insight into nutrient consumption and metabolism of production cell lines can greatly improve modelling accuracy and reduce scale-up risk.

The Eurofins BPT network of laboratories offers advanced spent media and complex raw material analysis to support upstream process development, reduce bioprocess variability, and accelerate time-to-market. Our proprietary SPEDIA™ platform delivers high-fidelity, quantitative metabolic data that strengthens model development, enables Process Analytical Technology (PAT) system validation, and supports data-driven optimisation strategies.

SPEDIA™ measures diverse analytes relevant to cell culture media

• Amino acids (10 μM–100 mM)
• Common saccharides (50 μM–100 mM)
• Common organic acids (50 μM–100 mM)
• Polyamines (10 μM–100 mM)
• Water-soluble B vitamins (0.1 μM–100 μM)
• Fatty acids
• Surfactants and buffers
• Inorganic salts and trace metals (ppm level)

These analyses are validated for mammalian, microbial, yeast, insect and complex media. New analytes are always in development.

Whether your goal is to improve cell line stability, increase yield, or support product filing, our SPEDIA™ targeted analytical platform delivers reliable data that empowers better decision-making and enables you to:

• Validate your in‑line Raman models
• Support digital twins, mechanistic models, and AI training
• Reveal actual nutrient depletion & metabolic dynamics
• Cover multianalyte quantification

Backed by years of experience and a proven track record with leading biopharma and biotech firms, Eurofins BPT ensures your spent media decisions are based on clear evidence.