Our expertise in chemical synthesis

With our state-of-the-art facilities and Quality by Design (QbD) approach, we provide comprehensive solutions for the synthesis of intricate chemical compounds tailored to meet the diverse needs of pharmaceutical, biotechnology, and research organizations. We can support your chemical synthesis requirements at all stages of the R&D pipeline.

adobestock_1389271426

Chiral synthesis

Eurofins CDMO is at the forefront of chiral synthesis, employing advanced techniques such as asymmetric synthesis, organometallic catalysis, enzymatic reactions, and chiral resolution. Our extensive experience in asymmetric hydrogenation, reduction, epoxidation, and enzymatic catalysis allows us to deliver complex chiral compounds with exceptional purity and efficiency.

We have successfully manufactured chiral compounds such as short peptides, chiral alcohols, chiral amino acids, chiral drug intermediates, new chemical entities, and chiral active pharmaceutical ingredients.

adobestock_665095196

Carbohydrate synthesis

Our specialized team excels in the synthesis of complex carbohydrate derivatives essential for clinical studies. Whether it’s monosaccharides, polysaccharides, iminosugars, carbocyclic sugars, or nucleosides, we have the knowledge and capabilities to deliver high-quality compounds with precision and efficiency.

We have expertise in the manufacturing of complex multi-step carbohydrates involving linear and convergent synthesis, selective protection and deprotection, control of regio and stereo selectivity, moisture-sensitive reactions, homogeneous and heterogeneous oxidation, and reduction reactions. We have capabilities in downstream purification and isolation involving water-soluble carbohydrates and their intermediates.

adobestock_53961365 (1)

Our expertise spans:

  • Route scouting and optimisation
  • Process development and scale-up (GMP compliance)
  • Advanced characterisation using NMR, FTIR, HPLC, LC-MS, and PSD analysis
  • Stability studies
  • Process safety assessment
  • Support for Investigational New Drug (IND) filings
  • Downstream purification and isolation pipeline