Discover how validated whole exome sequencing (WES) expands flexibility for genomic profiling across multiple sample types.

Whole exome sequencing (WES) is a powerful next-generation sequencing (NGS) approach for identifying disease-associated genomic variants that support biomarker discovery, precision medicine, and translational research. This white paper highlights the analytical validation of a WES assay using saliva, buccal swab, and whole blood, demonstrating robust analytical performance and matrix equivalency across all three sample types.

Key topics include:

• Analytical validation of a WES assay across saliva, buccal swab, and whole blood matrices
• Performance evaluation for sensitivity, specificity, positive predictive value, precision, stability, and limit of detection
• Matrix equivalency demonstrating comparable performance across multiple sample types
• Applications of validated WES workflows for genomic profiling, biomarker discovery, and precision medicine

As genomic technologies continue to advance, validated sequencing workflows are essential for generating reliable, clinically meaningful data. Discover how analytical validation and matrix equivalency studies can expand sample collection flexibility while supporting high-quality genomic profiling for clinical research and drug development.