Explore strategies for improving the sensitivity and reliability of cell-based neutralizing antibody (NAb) assays.

Accurate detection of neutralizing antibodies is essential for evaluating the immunogenicity of biologics and other advanced therapies. This webinar examines common sources of assay interference, including positional and matrix effects, and highlights practical strategies for minimizing variability and improving assay performance.

Topics include:

• Common sources of interference that can impact cell-based NAb assay performance
• Strategies for reducing positional and matrix effects to improve assay sensitivity
• The use of normalization approaches to enhance data accuracy and consistency
• A case study demonstrating the development of a cell-based NAb assay for an agonist therapeutic
• Applications of flow cytometry for cell-based neutralizing antibody assays

As biologics and advanced therapies continue to evolve, robust neutralizing antibody assays are essential for generating reliable immunogenicity data. Discover practical approaches for overcoming analytical challenges and improving confidence in cell-based NAb testing throughout clinical development.