Skin absorption: in vitro method
Enabling science. Ensuring compliance. Safeguarding ecosystems.
In vitro skin absorption studies (Franz cell method)
Precision insights for topical and transdermal product evaluation
Eurofins Agroscience Services India offers high-quality in vitro skin absorption studies using the Franz diffusion cell method, supporting the regulatory and product development needs of agrochemical, pharmaceutical, cosmetic, and chemical manufacturers. With robust experience and a commitment to compliance, our studies are conducted under GLP (Good Laboratory Practice) standards, ensuring global acceptance of your data for regulatory submissions.
Whether your compound is radiolabelled or non-radiolabelled (cold), our advanced analytical capabilities and experienced team ensure accurate, reproducible, and reliable assessment of percutaneous absorption and dermal bioavailability.
Our technical capabilities
Franz diffusion cell studies can be performed using human or animal skin and tailored to assess dermal absorption and permeation characteristics of your product.
- Radiolabelled studies (¹⁴C-compounds) supported by:
- LSC (Liquid Scintillation Counting)
- Radiochromatography
- Cold compound studies supported by:
- HPLC (High-Performance Liquid Chromatography)
- GC (Gas Chromatography)
- LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry)
Custom protocols can be developed based on your product requirements and regulatory expectations.
Why choose Eurofins Agroscience Services India?
- Extensive expertise in Franz cell assays.
- Capabilities for radiolabelled and cold compound testing.
- Advanced analytics: HPLC, GC, LC-MS/MS, LSC.
- GLP-compliant protocols with global regulatory alignment (OECD 428, etc.).
- Experienced team with proven regulatory study submissions worldwide.
Partner with Eurofins Agroscience Services India for trusted skin absorption testing
With a proven track record and world-class facilities, Eurofins Agroscience Services India is your ideal partner for skin absorption studies that meet global standards. Whether you're optimising a new topical formulation or completing a pesticide registration package, we offer scientific rigor, regulatory expertise, and unmatched data integrity.
One stop service – worldclass, worldwide
Frequently Asked Questions (FAQs)
The Franz diffusion cell method is a gold-standard in vitro approach for assessing the rate and extend of compound permeation through the skin, enabling accurate evaluation of dermal absorption and systemic exposure.
What types of compounds can you evaluate in skin absorption studies?
We assess both radiolabelled and cold (non-radiolabelled) compounds. Our team has experience working with agrochemicals, pharmaceuticals, cosmetics, biocides, and industrial chemicals.
Do you comply with regulatory guidelines for skin absorption studies?
Yes. Our studies are conducted under GLP conditions and in accordance with international guidelines such as OECD Test Guideline 428, ensuring acceptance by global regulatory bodies.
What skin models are available for testing?
We offer studies using human skin (when ethically sourced and available) as well as animal skin models, depending on regulatory requirements and compound characteristics.
Can you support full regulatory submissions with your data?
Absolutely. Our in-house Quality Assurance team ensures all data integrity and compliance, while our technical documentation supports regulatory submissions to authorities like EPA (Environmental Protection Agency), ECHA (European Chemicals Agency), OECD (Organisation for Economic Co-operation and Development), and national regulators worldwide.
Find a site near you!
Select Business Line
Select Country
Clear Filters
Reset Filters
Getting the map ready...
Failed to load the map