Cutting-Edge Technology Equipment Updates at EAS Easton
The Environmental Fate laboratory based at EAS Easton, Maryland, has recently increased its metabolite identification capabilities by investing in a state-of-the-art instrument, the Orbitrap Exploris 240 mass spectrometer.
This alternating polarity, high resolution (240,000 at m/z 200), high mass accuracy (sub ppm) in both MS and MS/MS modes instrument comes coupled to a Vanquish Flex 2-D UHPLC system and to a LabLogic β-RAM radio detector. This important technological enhancement will provide better sensitivity and lower levels of detection for testing materials.
While the EAS Easton laboratory has long been recognized for its high-quality standards and ability to handle difficult materials, this most recent update exemplifies our commitment to staying at the forefront of regulatory testing services. The equipped UHPLC system allows for fast on-line concentration of low abundant analytes and the separation of co-eluting compounds in one HPLC injection. The on-line β-RAM detector removes the metabolite ID uncertainty associated with comparing outputs from separate HPLC/β-RAM and LC/MS systems. When coupled with the Orbitrap’s high resolution and mass accuracy, this results in the unequivocal determination of radiolabeled unknowns.
Further, the new Orbitrap setup substantially increases the productivity potential and high-quality testing standards by reducing the screening and identification of unknown metabolites in test samples to a single LC/MS injection. In addition to the existing UHPLC-Bruker maXis Impact-I QTOF instrument and multiple Agilent UV/β-RAM HPLC systems, the new Orbitrap system ensures that the EAS Easton Environmental Fate laboratory remains your laboratory of choice for regulatory testing.
EAS Easton provides global clientele with GLP studies that meet regulatory requirements for the testing of agrochemicals, industrial chemicals, consumer products, pharmaceuticals, biocides and animal health products. Formerly known as Wildlife International, this laboratory and its team of expert scientists are intimately involved in the development of guidance and constantly engage in scientific exchanges in OECD, EPA, PMRA, and other regulatory programs.