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Small Molecules - API Development & Manufacturing >> Solid State Research and Development >> Salt or Co-Crystal Screening

Salt or Co-Crystal Screening

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Salt and co-crystal screening are reliable solutions in modern drug development to address some undesirable properties such as low solubility, chemical instability and high hygroscopicity in APIs. Utilizing High-Throughput Screening (HTS) technologies, we investigate formation of salts/co-crystals with pharmaceutically acceptable salt and co-formers in different solvent mixtures. This screening approach provides us with a quick identification of lead candidates which then will be prepared for complete characterization.

Related instruments: Unchained LabsJunior™, Bruker D8 Discover™

 

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