Eurofins ADME Bioanalyses SAS

Eurofins ADME BIOANALYSES has been a Eurofins expert in pharmacokinetics and metabolism since 1987.

The laboratory is equipped with a LIMS Watson® coupled with ReportDesigner®.

Our bio-analytical team supports discovery, preclinical and clinical studies with method development, validation, and sample analysis in biological matrices for both small and large molecules (peptides, antibodies, other proteins) and Biomarkers with LC-MS/MS, Immunoassays and Immunogenicity assessment studies.

Services:

• Bioavailability and Blood Brain Barrier permeability screening tests
• ADME studies with radiolabelled molecules (14C or 3H)
• Development and validation of analytical methods in biological fluids and tissues according to FDA and EMA guidelines
• Bioanalysis to support pre-clinical and clinical trials for both small and large molecules
• Pharmacokinetics calculations and interpretation
• Immunogenicity
• Biomarker analysis
• Specific expertise on bioequivalence studies and drug-drug interaction studies
• Protein-binding studies
• Dermal distribution and absorption studies on Franz cells or Bronaugh cells and Release tests for formulations with membranes

Specific expertise:

• Biomarker Panels
• ADC analysis
• Dermal distribution and absorption studies and IVRT
• Radiolabelled ADME studies

Accreditations:

GLP compliant - successfully inspected by FDA on a bioequivalence study and inspected every two years by EMA.