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Clinical efficacy

Always on the safe side

Index:

Skincare

Hygiene Products

Hair Care

Sun Care

Oral Care

Make-up

This list is not exhaustive. Eurofins can perform customized developments to your existing protocols or develop new ones from scratch.


Skincare

Moisturization

Title

Instrumental assessment of the immediate or cumulative moisturizing efficacy

Objective

To assess the efficacy of a product on the hydration level of the upper layers of the epidermis after single or repeated applications

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: 1 day for immediate efficacy and XX days for cumulative efficacy. (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Measurement of the skin capacitance using Corneometer ®, Moisturemeter®D  and/or skin water content. Picture with Visioscan® V98

Procedure

Immediate efficacy:

Basal corneometric measurements on 2 sites

Controlled application of the product to one site

Post treatment corneometric measurements on test and control sites (kinetics: 30 min. / 2h / 4h / 6h / 8h /10h /12h /24h and/or 48h)

Statistical comparison of the results obtained on the control and test sites at each experimental time

Cumulative efficacy:

Basal corneometric measurements

Use of the product at home by the subjects following the instructions for use

Post treatment corneometric measurements

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Skin Barrier Function / Protection

Title

Instrumental assessment of the efficacy on the skin barrier function

Objective

To assess the effects of a product on the skin barrier function after single or repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: XX days (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Measurement of the transepidermal water loss (TEWL) (Tewameter® or VapoMeter®, or Evaporimeter Ep-1) reflecting stratum corneum barrier functions

Procedure

Immediate efficacy:

Basal TEWL measurements on 2 sites

Controlled application of the product to one site

Post treatment TEWL measurements on test and control sites (kinetics: 30 min. / 2h / 4h / 6h / 8h /10h /12h 24h and/or 48h)

Statistical comparison of the results obtained on the control and test sites at each experimental time

Cumulative efficacy:

Basal TEWL measurements

Use of the product at home by the subjects following the instructions for use

Post treatment TEWL measurements

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Soothing Effect on SLS induced redness

Title

Instrumental assessment of the soothing efficacy after induction of erythema by application of SLS solution under occlusive patch

Objective

To assess the soothing efficacy of a product versus a reference product after repeated applications to skin previously irritated by application of SLS solution under occlusive patch

Schedule

Duration of the study: 24 hours

Beginning: 3 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Colorimetric measurement by means of Spectrophotocolorimeter® or Mexameter® or Colorimeter® of the erythematous skin reaction induced by application of diluted solution of Sodium Laury Sulfate (2%) under occlusive patch, and evolution over the time after product application

Procedure

Preselection-test to determine volunteers presenting with reactivity to SLS, under a Dermatologist control* (at least 7 days before the beginning of the study)

Erythema induction on a predefined area on the volunteer’s forearm by applying diluted solution of Sodium Lauryl Sulfate (2%) under a Finn Chamber occlusive patch for 24 hours (1 test site by tested product, one SLS control area, one water control area)

Patches removal 24 hours after the patches application (the volunteer’s forearm is gently rinsed with water and dried out with a tissue by slight pressure)

Basal colorimetric measurements on the experimental sites (1 test site and 2 control sites)

Standardized tested product application (20µL) on the induced erythema on the tested site

Colorimetric measurements on each experimental sites (test and control) at different kinetics (30 minutes, 2h, 4h and 24h after application for example)

Statistical comparison of the results obtained with and without treatment for each product, at each experimental time

*Optional

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Soothing Effect: Anti-Redness / Anti-Red Blotches

Title

Instrumental assessment of the soothing efficacy on pre-existing skin redness

Objective

To assess the soothing/anti-redness efficacy of a product after repeated applications

Schedule

Duration of the study: XX days

Beginning: 3 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Colorimetric measurement by means of Spectrophotocolorimeter® or Mexameter® or Colorimeter® of the erythematous skin reaction (non-immunological reaction) induced by a short UVB exposure and evolution over the time after product application or pictures with Visia CR®

Procedure

Colorimetric measurements or pictures with Visia CR®

Application of the product

Statistical comparison of the results obtained before and after treatment

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Soothing Effect: Stinging Test

Title

Assessment of the soothing efficacy

Objective

To assess the non-stinging efficacy of a product after single application under controlled conditions

Schedule

Duration of the study: 3 days

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after end of the study

Methodology

Self-evaluation of the stinging intensity according to an ordinal scale, or using Spectrophotocolorimeter®

Procedure

Basal stinging test:

                - Facial sauna for 15 minutes

                - Application of a 10% lactic acid aqueous solution to one nasogenian fold and application of a 0.9% sodium chloride aqueous solution to the other nasogenian fold

                - Self-assessment by the subjects of the stinging intensity within 5 minutes after application of each solution

Application of the product 2 days later

Post application stinging test

Statistical comparison of the results obtained before and after product application

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Dermo-Protection

Title

Instrumental assessment of the dermo-protective efficacy

Objective

To assess the dermo-protective efficacy of a product after single application under controlled conditions

Schedule

Duration of the study: 1 day

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after end of the study

Methodology

Assessment of the stratum corneum integrity by measurement of the transepidermal water loss (TEWL) (Tewameter® or VapoMeter®, or Evaporimeter®)

Procedure

Basal measurements of TEWL on 2 sites

Application of the product at the investigating centre to one site

1 or 2 or 3 hour-post application TEWL measurements on the test and control sites

Statistical comparison of the results obtained on the control and test sites before and after application

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Skin Temperature

Title

Assessment of the cooling / warming efficacy

Objective

To assess the cooling/warming efficacy of a product after single application under controlled conditions

Schedule

Duration of the study: 1 day

Beginning: 2 weeks upon receipt of the samples

Report: 2 weeks after the end of the study

Methodology

Measurement of the skin temperature by means of Infrared Camera

ThermaCAM®B2 or Infrared Camera FLIR® system or infrared thermometer (Fluke® 566) or Skin Thermometer® ST 500

Procedure

Controlled acclimatization period

Measurement on the 2 defined sites

Application of the product to one site

Post application measurement on both test and control sites

Statistical comparison of the results obtained at each experimental time on the control and test sites

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Protection against cold

Title

Assessment of the protection against cold

Objective

To assess the protection against cold of a product after single application under controlled conditions

Schedule

Duration of the study: 1 day

Beginning: 2 weeks upon receipt of the samples

Report: 2 weeks after the end of the study

Methodology

Measurement of the skin temperature by means of Infrared Camera ThermaCAM®B2 or Infrared Camera FLIR® system or infrared thermometer (Fluke 566) or Skin Thermometer® ST 500

Procedure

Controlled acclimatization period

Measurement on the 2 defined sites

Application of the product to one site

Exposition of the 2 sites to cold

Post application measurement on both test and control sites

Statistical comparison of the results obtained at each experimental time on the control and test sites

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN

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Skin Viscoelastic Properties (Firmness / Suppleness / Elasticity / Tonicity / Tensor / Lift)

Title

Instrumental assessment of the efficacy of a cosmetic product on the skin viscoelasticity

Objective

To assess the skin viscoelastic properties after a product application in normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: 1 day or several days depending on the product efficacy

Beginning: 2 weeks upon receipt of the samples

Report: 4 weeks after the end of the study

Methodology

Measurement of the skin viscoelastic properties using a Cutometer®

Procedure

Basal cutometric measurements

Single application of the product at the investigating centre or repeated applications at home

Immediate post application cutometric measurements on both test and control sites or after X days of daily application

Statistical comparison of the results obtained before and after product application and on the test and control sites

Optional: cosmetic qualities and efficacy questionnaire

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Anti-Wrinkles

Title

Instrumental assessment of the anti-wrinkle efficacy

Objective

To assess the anti-wrinkle efficacy of a product after repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: XX days (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Analysis of Silflo® replicas of the crow’s feet wrinkles with the Quantirides®/ Quantilines® software or Visioline® VL 650 software or fringes projection analysis with Dermatop HE® or AEVA®

Procedure

Basal skin replica. Measurement with fringe projection device

Use of the product at home by the subjects following the instructions for use

Post treatment replicas of the same crow’s feet wrinkles and measurement

Analysis of the parameters of the wrinkles

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Professional pictures

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Face Volume (Face sagging, lips volume, eye bags)

Title

Instrumental assessment of the efficacy on face volumes

Objective

To assess the face-volume efficacy of a product after single or repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration: 1 day or XX days (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Fringes projection analysis with Dermatop HE® or AEVA®

Procedure

Basal measurements

Post treatment measurements of the same crow’s feet wrinkles/fine lines and cutometric measurements

Analysis of the parameters

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Measurement of the skin whitening (Colorimeter®)

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Skin Regeneration

Title

Instrumental assessment of the regenerating efficacy

Objective

To assess the regenerating efficacy (renewal of epidermal cells) of a product after repeated applications under normal conditions of use

Schedule

Duration of the study: 2-5 weeks

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Assessment of the cell turn-over by comparing the kinetics of decrease in skin colour obtained by application of DHA (Dihydroxyacetone) to a skin site treated with the product and to a control site by means of colorimetry (Mexameter® or Colorimeter®  or Spectrophotocolorimeter®)

Procedure

Basal colorimetric measurements on 2 sites

Application of a product containing DHA under patch on the 2 sites

Colorimetric measurements after patch removal

Daily application of the product to one pre-colored site

Daily colorimetric measurements on test and control site until coloration has disappeared

Statistical comparison of the results obtained from both test and control sites

Optional:

DHA test after treatment by the product under normal conditions of use

Professional pictures before and after treatment

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Slimming

Title

Instrumental assessment of the slimming efficacy

Objective

To assess the slimming efficacy of a product after repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: XX days (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Evaluation of slimming effect by fringe projection analysis AEVA®, weighing of the subjects and/or measurements of various body parts (thighs, waist, haunch…) in centimetres using a dressmaker meter

Procedure

Basal measurements of body weight and dimensions

Use of the product at home by the subjects following the directions for use

After treatment measurements of body’s weight and dimensions

Statistical comparison of the results obtained before and after treatment

Optional:

Infra-red thermographic measurements (Infrared Camera ThermaCAM®B2) before and after treatment (EVIC France)

Cosmetic qualities and efficacy questionnaire

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Smoothing Effect / Orange Peel Aspect

Title

Assessment of the smoothing effect / orange peel aspect

Objective

To assess the anti-cellulitis efficacy of a product after repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: XX days (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Clinical assessment of the state of the skin surface (“orange peel aspect”) on thighs according to an ordinal scale defined by the investigating centre and/or thermographic measurements (Infrared Camera ThermaCAM®B2), or fringes projection analysis AEVA®

Procedure

Basal clinical scoring and/or thermographic measurement

Use of the product at home by the subjects following the directions for use

Post treatment clinical scoring and/or thermographic measurement and/or AVEA®

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Self-Tanning Effect

Title

Instrumental assessment of the self-tanning efficacy

Objective

To assess the self-tanning efficacy of a product after single/repeated application.

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: 1 or several days depending on the action mode of the product.

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Assessment of the skin colour induced by the product by means of colorimetric measurements (Mexameter® or Colorimeter® or Spectrophotocolorimeter®)

Procedure

Basal colorimetric measurements

Single or repeated application of the product at the investigating centre

Post treatment colorimetric measurements at different times in order to obtain the kinetics curve of the tan achieved

Statistical comparison of the results obtained before and after treatment

 

Optional: cosmetic qualities and efficacy questionnaire

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Self-Tanning / Accelerating or Lasting

Title

Instrumental assessment of the tanning accelerating effect and the lasting efficacy

Objective

To assess the tanning accelerating and/or lasting efficacy of a product after repeated application, simulating the use intention

Schedule

Duration of the study: 4 weeks

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Assessment of the speed of obtaining a skin tan by means of colorimetric measurements (Mexameter® or Colorimeter® or Spectrophotocolorimeter®)

Assessment of the lasting tanning effect

Procedure

Determination of the theoretical lowest UVA dose capable of inducing an immediate and persistent minimal pigmentary response (MPPD)

Basal measurement of the skin colour on 4 sites of the subjects’ back

Repeated application of the product in 2 sites, once a day during 5 to 10 days, at the investigating centre

Measurement of the skin colour on the 4 sites (test and control) delimited on the subjects’ back

Induction of skin pigmentation in daily sessions of UVA radiations (Sun Simulator Multiport® -Solar Light Co) – 1 MPPD/day – during 3 to 5 days in 2 sites: one site with product application and one site without product application

Colorimetric measurements on all 4 sites on both test (with and without radiation) and control sites (with and without radiation) each day of radiation

For tanning accelerating effect:

Repeated colorimetric measurements on all 4 sites 3 days later

For lasting tanning effect:

Repeated colorimetric measurements on all 4 sites every 3 days for 10 days

Statistical comparison of the results obtained on both control and test areas

Optional: Prolonged effect of the tan with additional product applications

Production laboratory

  • Eurofins EVIC France, Bordeaux, France
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Sebo-Regulation / Sebum

Title

Instrumental assessment of the sebo-regulating efficacy

Objective

To assess the efficacy of a product on the sebum secretion after repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: at least 28 days (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Measurement of the sebum secretion on the forehead using the Sebumeter® and Sebutape® or Sebufix® technique and analysis of the images with Quantiseb® or Visioscan VC 98® or Visioline® VL 650 or Skin Visiometer® SV 600 software

Procedure

Basal measurement of the sebum secretion

Use of the product at home by the subjects following the instructions for use

Post treatment measurements of the sebum secretion

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN

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Sebum Rate / Matifying Effect

Title

Instrumental assessment of the effect on the sebum rate / matifying efficacy

Objective

To assess the effect of a product on the sebum rate / matifying efficacy after single or repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: 1 day for immediate efficacy and at least 28 days for long term effect (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Measurement of the sebum rate using the Sebumeter®and/or glossymeter, Visia CR pictures analysis

Procedure

Immediate efficacy:

Basal measurements on 2 sites

Controlled application of the product to one site at the investigating centre

Post treatment measurements on test and control sites (kinetics: 2h / 4h /8h /10h /12h)

Statistical comparison of the results obtained before and after the treatment and on the control and test sites

Long term efficacy:

Basal measurements

Use of the product at home by the subjects following the instructions for use

Post treatment measurements

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Intermediate controls

Evaluation versus control product

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Comedolytic Effect

Title

Clinical assessment of the comedolytic efficacy

Objective

To assess the comedolytic efficacy of a product after repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: at least 28 days

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Counting of the retentional and/or inflammatory elements

Procedure

Basal counting of the retentional and/or inflammatory elements on the forehead and cheeks or whole face

Use of the product at home by the subjects following the instructions for use

Post treatment count of the retentional and/or inflammatory elements (Comedolytic effect: capability to reduce the number of elements)

Optional:

Cosmetic qualities and efficacy questionnaire

Professional pictures

Statistical analysis of the data

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Lightening / Whitening

Title

Instrumental assessment of the depigmenting efficacy on dark spots (including senescence spots)

Objective

To assess the depigmenting efficacy of a product after repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: 28 days (at least) – 56 days (advised)

(Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Assessment of the skin color of dark spots by colorimetric measurements using the Mexameter® or Colorimeter® or Spectrophotocolorimeter® or standardized photography with Visa CR®

Procedure

Basal colorimetric measurements of a distinctive dark spot and surrounding area

Pictures with Visia CR®

Use of the product at home by the subjects following the directions for use

Post treatment colorimeter measurement of the same areas and pictures

Statistical comparison of results obtained (Mexameter®: melanic index / Spectrophotocolorimeter® or Colorimeter®: L*= brightness (luminescence) and “ITA°”= individual typological angle parameters) before and after treatment

Analysis of the picture

Optional:

Cosmetic qualities and efficacy questionnaire

Professional pictures before and after treatment

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Hygiene Products

Moisturization

Title

Instrumental assessment of the immediate or cumulative moisturizing efficacy

Objective

To assess the efficacy of a product on the hydration level of the upper layers of the epidermis after single or repeated applications

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: 1 day for immediate efficacy and XX days for cumulative efficacy. (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Measurement of the skin capacitance using Corneometer®, Moisturemeter®D  and/or skin water content. Picture with Visioscan® V98

Procedure

Immediate efficacy:

Basal corneometric measurements on 2 sites

Controlled application of the product to one site

Post treatment corneometric measurements on test and control sites (kinetics: 30 min. / 2h / 4h / 6h / 8h /10h /12h /24h and/or 48h)

Statistical comparison of the results obtained on the control and test sites at each experimental time

Cumulative efficacy:

Basal corneometric measurements

Use of the product at home by the subjects following the instructions for use.

Post treatment corneometric measurements

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Skin Barrier Function / Protection

Title

Instrumental assessment of the efficacy on the skin barrier function

Objective

To assess the effects of a product on the skin barrier function after single or repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: XX days (Optional: intermediate controls)

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Measurement of the transepidermal water loss (TEWL) (Tewameter® or VapoMeter®, or Evaporimeter Ep-1) reflecting stratum corneum barrier functions

Procedure

Immediate efficacy:

Basal TEWL measurements on 2 sites

Controlled application of the product to one site

Post treatment TEWL measurements on test and control sites (kinetics: 30 min. / 2h / 4h / 6h / 8h /10h /12h 24h and/or 48h)

Statistical comparison of the results obtained on the control and test sites at each experimental time

Cumulative efficacy:

Basal TEWL measurements

Use of the product at home by the subjects following the instructions for use.

Post treatment TEWL measurements

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Peeling / Exfoliating Effect

Title

Instrumental assessment of the peeling/exfoliating efficacy

Objective

To assess the peeling/exfoliating efficacy of a product after single application

Schedule

Duration of the study: 1 day

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Determination of the desquamation index based on the analysis of the scales extracted from the skin (D-Squame® & Quantisquames® software, or Corneofix® technique & Visioscan VC 98®, Skin Visiometer® or Visioline® VL 650 software)

Procedure

Basal skin stripping with D-Squame® or Corneofix® adhesives on 2 sites

Single application of the product at the investigating centre to one site

Post treatment skin stripping on both test and control sites

Statistical comparison of the results obtained before and after treatment

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Deodorant – Sniff Test

Title

Olfactive assessment of the deodorant efficacy, Sniff test

Objective

To assess the deodorant efficacy of a product after single application

Schedule

Duration of the study: 2-3 days after a wash-out period

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Olfactive assessment of the body odour by trained and qualified examiner(s)

Procedure

Washing of both armpits of the subjects with neutral soap

Olfactive assessment of both armpits

Controlled application of the product to one of the armpits

Olfactive assessment at different times (4h and/or 6h and/or 8h and/or 24h and/or 48h) of both armpits (test and control)

Statistical comparison of the results obtained on the test and control sites at each experimental time

Optional:

Possibility to adapt this technique to feet

Microbiological analysis

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Deodorant – Anti-white Marks

Title

Assessment of the non-transfer ability of the product (i.e. white marks transfer to the clothes)

Objective

To assess the ability of a deodorant not to lead to white marks on clothes after a single application under controlled conditions

Schedule

Duration of the study: 1 day

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Clinical assessment to black clothes by a trained assessor in 20 volunteers

Procedure

Application of the product to one armpit,under standard conditions

To the contro-lateral armpit, application of a negative reference (not leaving any white mark)

Leave-on time

The volunteer is asked to put on a standard thigh t-shirt in 100% black cotton

Then the shirt is removed and graded by a clinical trained assessor for its white marks to both right and left sides

Option : The volunteers stay 2 hours at the center, wear a large suit, then the methodology is carried out again 2 hours later

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Dedodorant – Anti-Yellow Marks

Title

Assessment of the anti-yellow stains efficacy  of deodorant

Objective

To assess the ability of a deodorant not to lead to yellow marks on clothes after repeated applications and washing of the clothes

Schedule

Duration of the study: 21 days

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Clinical assessment to white clothes by a trained assessor in 20 volunteers

Procedure

Application of the product to one armpit,under standard conditions, everyday, by the subject, at home

To the contro-lateral armpit, application of a known negative reference (not leaving any yellow mark).

The volunteer is aked to wear a a standard thight t-shirt in 100% white cotton, everyday, for 21 days,under her/his clothes (2 peces provided) and to wash it in a regular way under specific given conditions (detergent, temperature etc…)

Then the shirts are brought back after 21 days and graded by a clinical trained assessor for their yellow marks to both right and left sides

Production laboratory

  • Eurofins ATS, Aix-en-Provence, France
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Antiperspirant - Gravimetry

Title

Assessment of the antiperspirant efficacy

Objective

To assess the efficacy of a product on the excretion by the sweat glands after repeated applications

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: 5-28 days after a 17 day wash-out period

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Gravimetric assessment: weighing of collected sweat based on the FDA method

Procedure

Aggravated sudation period in an overheated room for 2 periods of 20 minutes with pads placed under each armpit of the subjects

Weighing of collected sweat pads

Wash of armpits with a neutral soap

Application of the product to one armpit

Use of the product at home following the directions for use on one armpit for 5 to 28 consecutive days

Gravimetric measurements in the same previous conditions on both armpits

Statistical comparison of the results obtained on test and control sites before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Daily application of the product at the investigating centre

Additional gravimetric measurements

Possibility to adapt this technique to feet

Production laboratory

  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins EVIC Romania, Bucharest, ROMANIA


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Antiperspirant - TEWL

Title

Assessment of the antiperspirant efficacy

Objective

To assess the efficacy of a product on the excretion by the sweat glands after single application

Schedule

Duration of the study: 1 day

Beginning: 2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Measurement of the trans-epidermal water loss by means of Tewameter® or VapoMeter®, or Evaporimeter®

Procedure

Basal measurements of the TEWL on each armpit

Application of the product to one armpit at the investigating centre

8 hours after application of the product: measurement of the TEWL on both test and control armpits

Statistical comparison of the results obtained on test and control sites before and after treatment

Optional: Additional measurements

Production laboratory

  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Hair Care

Efficacy of Haircare products by hairdressers

Title

Assessment of the hair care products efficacy by professional hairdressers

Objective

The objective will depend on the requested efficacy measurement

Schedule

Duration of the study: will depend on the study

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Please contact us for detailed offer

Procedure

The procedure will depend on the requested efficacy measurement

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA


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Anti-Hair Loss / Hair Regrowth

Title

Instrumental assessment of the anti-hair loss/hair regrowth efficacy

Objective

To assess the anti-hair loss/hair regrowth efficacy of a product versus placebo, in single or double blind, after repeated application under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: depending on the product (minimum advised: 3 months of treatment)

Beginning: 3/4 weeks upon receipt of the samples

Report: 4 weeks after the end of the study

Methodology

Counting of anagen and telogen hair and/or examination of the hair diameter and growth rate and/or scoring of the scalp and hair characteristics using the technique of phototrichograms

Procedure

Basal phototrichogram and/or examination of the hair diameter and growth rate and/or scoring of the scalp and hair characteristics

1st application of the product and placebo at the Investigating center

Use of the product or placebo at home by the subjects following the instructions for use

Post treatment phototrichogram and/or examination of the hair diameter and growth rate and/or scoring of the scalp and hair characteristics

Statistical comparison of the results obtained before and after treatment for each product

Optional:

Cosmetic qualities and efficacy questionnaire

Application of the product and placebo at the investigating centre under controlled conditions

Intermediate controls

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Anti-Dandruff

Title

Assessment of the anti-dandruff efficacy

Objective

To assess the anti-dandruff efficacy of a product after repeated applications under normal conditions of use

Optional: To assess subjectively its cosmetic qualities and efficacy

Schedule

Duration of the study: depending on the product (at least 14 days of treatment)

Beginning: 3 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Clinical assessment of the dandruff state according to the ordinal scale defined by the investigating centre and/or gravimetric measurements (weighing of dandruff collected from the rinsing water)

Procedure

Basal scoring of the dandruff state and/or gravimetric measurements

Use of the product at home by the subjects following the instructions for use

Post treatment scoring of the dandruff state and/or gravimetric measurements

Statistical comparison of the results obtained before and after treatment

Optional:

Cosmetic qualities and efficacy questionnaire

Study versus placebo

Application at the investigating centre under controlled conditions

Intermediate controls

Controlled wash-out period before treatment

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Sun Care

Sun Protection Factor (SPF)

Title

Assessment of the Sun Protection Factor according to the ISO 24444 and FDA 2011

Objective

To define the sun protection level of a product by the calculation of the sun protection factor (SPF)

Schedule

Duration of the study: 1-2 weeks depending on the stages chosen by the Sponsor

Beginning: 1-2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Clinical assessment of the skin erythemal response to ultraviolet radiation (Sun Simulator Multiport®)

Procedure

Determination of the theoretical Minimal Erythema Dose (MED) to define the UV exposure time

Application of the product and reference product to the back of the subjects

Determination of the current Minimal Erythemal Dose (MED)

UV exposure 15-30 minutes after application

Skin examination 16 to 24 hours after UV exposure: clinical assessment

Optional:

SPF determination according to FDA final monograph (1999) / Australian/New Zealand standard recommendations (AS/ZNS 26094: 1998)

Screening or full study performance

Production laboratory

  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Sun Protection Factor + Water Resistance (SPF + WR)

Title

Assessment of the Sun Protection Factor according to the ISO 24444 and

Assessment of Water Resistance according to the COLIPA GUIDELINES FOR EVALUATING SUN PRODUCT WATER RESISTANCE -December 2005

Objective

To define the sun protection level of a product by the calculation of the sun protection factor (SPF) and to assess its water resistance (WR) by means of the calculation and comparison of the SPF before immersion into water and after an immersion period.

Schedule

Duration of the study: 1-2 weeks depending on the stages chosen by the Sponsor

Beginning: 1-2 weeks upon receipt of the samples

Report: 3-4 weeks after the end of the study

Methodology

Clinical assessment of the skin erythemal response to ultraviolet radiation (Sun Simulator Multiport®) before and after immersion into water

Procedure

Determination of the theoretical Minimal Erythemal Dose (MED) to define the UV exposure time

Shower of the subjects

Application of the product to the back of the subjects on the immersed site

Jacuzzi (2 x 20 minutes)

UV exposure of the immersed site

Application of the product and reference product on non-immersed sites

Determination of the current MED

UV exposure 15-30 minutes after application

Skin examination 16 to 24 hours after UV exposure: clinical assessment

Optional: Very Water Resistance test (Jacuzzi 4 x 20 minutes)

Production laboratory

  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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p-UVA

Title

Assessment of the Protection Factor against ultraviolet A radiation (UVA) according to the UVA ISO 24442

Objective

To define the sun protection level of a product by the calculation of the UVA sun protection factor (PFA)

Schedule

Duration of the study: 1-2 weeks depending on the stages chosen by the Sponsor

Beginning: 1-2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Clinical assessment of the skin pigmentary response to UVA ultraviolet radiation (Sun Simulator Multiport®)

Procedure

Determination of the theoretical lowest UVA dose capable of inducing an immediate and persistent minimal pigmentary response (MPPD)

Application of product and reference product to the back of the subjects

UV exposure 15-30 minutes after application

Skin examination between 2 and 4 hours after UV exposure (according to the expected PFA value): clinical assessment

Production laboratory

  • Eurofins EVIC France, Bordeaux, FRANCE
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Oral Care

Teeth Whitening

Title

Assessment of the teeth whitening

Objective

To assess the skin whitening and the efficacy of a product after single or repeated application(s) under normal conditions of use

Schedule

Duration of the study: 1 days or X days

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Instrumental analysis of the teeth whitening on UV pictures with Visia CR® or Nikon® D300 Micro Nikkor AF-S 105mm and clinical scoring by a dentist

Procedure

Basal picture and clinical scoring (using shade grading system)

Single or repeated use

Analysis of the whitening effect

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Anti-Plaque

Title

Assessment of the anti-plaque efficacy

Objective

To assess the anti-plaque activity of a product after single or repeated application(s) under normal conditions of use

Schedule

Duration of the study: 1 day or X days

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Measurements of the FMPS (Full-Mouth Plaque Score), of the Plaque Index (PI) and of the Gingival Index (GI)

Evaluation of visible plaque with disclosing tablets

Pictures of the teeth with Nikon d300 Micro Nikkor AF-S  105 mm

Procedure

Pictures and clinical scoring before and after the treatment

Single or repeated use

Analysis of the anti-plaque effect

Production laboratory

  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA
  • Eurofins EVIC Spain, Barcelona, SPAIN


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Anti-Tartar

Title

Assessment of the anti-tartar efficacy

Objective

To assess the anti-tartar activity of a product after single or repeated application(s) under normal conditions of use

Schedule

Duration of the study: 1 day or X days

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Measurements of the CSI (Calculus Surface Index) and of the Gingival Index (GI)

Pictures of the theets with Canon Powershot G6

Procedure

Pictures and clinical scoring before and after the treatment

Single or repeated use

Analysis of the anti-tartar effect

Production laboratory

  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA

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Teeth Hypersensitivity

Title

Assessment of the efficacy against teeth hypersensitivity

Objective

To assess the activity of a in reducing teeth hypersensitivity after single or repeated application(s) under normal conditions of use

Schedule

Duration of the study: 1 day or X days

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Measurements of teeth sensitivity to warm and cold stimulus by VAS (Visual Analogue Scale) and objective evaluation (clinical scoring)

Procedure

VAS and clinical scoring before and after the treatment

Single or repeated use

Analysis of the teeth hypersensitivity reduction effect

Production laboratory

  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA


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Anti-Bacterial (Mouth)

Title

Assessment of the antibacterial efficacy on the mouth

Objective

To assess the antibacterial activity of a product after single or repeated application(s) under normal conditions of use

Schedule

Duration of the study: 1 day or X days

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Quantification of periodontal bacteria

Procedure

Periodontal DNA test kit (Curaden) before and after the treatment

Single or repeated use

Analysis of the anti-bacterial effect

The procedure may be different depending on the laboratory

Production laboratory

  • ·Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA


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Anti-Halitosis

Title

Assessment of the anti-halitosis efficacy

Objective

To assess the anti-halitosis activity of a product after single or repeated application(s) under normal conditions of use

Schedule

Duration of the study: 1 day or X days

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Measurements of the VSC (Volatile Sulphur Compounds), by Halimeter®

Procedure

Measurements of the VSC before and after the treatment

Single or repeated use

Analysis of the anti-halitosis effect

The procedure may be different depending on the laboratory

Production laboratory

  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA


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Make-up

Waterproof

Title

Assessment of the Waterproof efficacy

Objective

To assess the waterproof efficacy of a product, after a single and standardized application, and standardized pulverisations, under controlled conditions

Schedule

Duration of the study: 1 day

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Clinical scoring by a beautician

Procedure

Product application by a beautician, according to a right-left randomization

15 minutes of leave-on time

Water pulverization

Clinical assessment by a beautician

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA


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Smudgeproof

Title

Assessment of the anti-smudge efficacy

Objective

To assess the anti-smudge efficacy of a product, after a single and standardized application, under controlled conditions

Schedule

Duration of the study: 1 day

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Clinical scoring by a beautician

Procedure

Product application by a beautician, according to a right-left randomization

15 minutes of leave-on time

Facial sauna which releases steam at 42°C, during 6 minutes

Clinical assessment by a beautician

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA

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Long Lasting

Title

Assessment of the long lasting efficacy

Objective

To assess the long Lasting efficacy of a cosmetic product after a single and standardized application

Schedule

Duration of the study: 1 day or X days

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Instrumental analysis of the lasting on pictures with Visia CR® and clinical scoring by a beautician

Procedure

Application of the product by a beautician

Basal picture and clinical scoring (using analogical scale)

Rest period of the volunteers (controlled conditions)

Pictures on different kinetics Tx

Analysis of the lasting using the Kalliste software (lasting of the made-up surface) or Colorskin Software (color lasting)

Analysis of the lasting by clinical scoring

The procedure may be different depending on the laboratory

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA


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Make-up Removal

Title

Assessment of the make-up removal efficacy

Objective

To assess the make-up removal efficacy of a product after a single and standardized application

Schedule

Duration of the study: 1 day

Beginning: 2 weeks upon receipt of the sample

Report: 3-4 weeks after the end of the study

Methodology

Clinical scoring by a beautician and assessment of the cosmetic qualities of the product by the volunteers using a suitable questionnaire

Procedure

Application of 3 or 4 make-up products by a beautician

Leave-on time of 15 minutes

Make-up removal of an half-face by a beautician

Clinical assessment by a beautician

Make-up removal of the other half-face by the volunteer

Assessment of the cosmetic qualities by the volunteer

Production laboratory

  • Eurofins ATS, Aix-en-Provence, FRANCE
  • Eurofins BioPharma Product Testing, Rome, ITALY
  • Eurofins EVIC Romania, Bucharest, ROMANIA


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Experts Scoring on all product types

Criteria

Skin

Face – body

 

 

 

Smoothness

Softness

Dryness

Firmness

Texture (pores)

Matifying effect

Imperfections

Redness

Cellulite

Stretch marks

Wrinkles

Suppleness

Radiance

Long lasting of foundation

Teeth

Whitening effect

Tartar scoring

Removal of dental plaque

Stain scoring

Eyes

 

Dark circles under the eyes

Bags under the eyes

Long lasting of makeup (Eye shadow, mascara, eye liner)

Hair

 

Dandruffs

Regrowth

Anti-hair loss

Depilatory (velocity and quality of the hair regrowth)

Bleaching effect

Nails

 

Coating effect

Long lasting effect of nail enamel

Brightness

Ribbed

Softness

Brittleness

Split scoring

Lips:

 

 

Long lasting effect of make up

Dryness

Volume

Feet

Dryness

Crack scoring

Callosity scoring


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Locations
Cosmetics Laboratories
Map of cosmetics testing laboratories

 

Clients