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Discovery >> Services >> Preclinical

More than 250 preclinical models, supporting:

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Anti-Infectives/Microbiology Inflammation/Allergy Cardiovascular CNS / Pain
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Gastrointestinal/Renal Oncology Metabolic/Endocrine Respiratory
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 DMPK  Safety    

Trust the experts at Eurofins with the preclinical assessment of your most promising candidates

Eurofins has a long and successful history of creating and testing  models to evaluate the pharmacological effects of drug candidates in all major therapeutic categories. We emphasize and excel at anti-infectives, inflammation/allergy, CNS/pain and oncology.

Our portfolio provides progressive evaluation of your study from tolerability and exposure through all levels of pharmacodynamics, including primary screening for activity and rank-ordering, lead identification, candidate selection, disease-specific efficacy and dose-dependent proof-of-concept in relevant translational studies.

We provide therapeutically focused disease models, incorporating biomarkers and outcome measures that enable greater prediction of clinical success. Like our in vitro services, our in vivo studies are supported by a dedicated team of global Technical Directors specializing in specific therapeutic areas. Our scientific experts, with their years of pharmaceutical drug development expertise, provide you ongoing project oversight, with prompt communication and a commitment to on-time reporting, enabling you to meet your strict drug-development timelines.

Our experienced, expert staff can formulate and dose test articles by virtually any route, including short- or long-term continuous infusion, and can monitor blood, brain, tissue and/or CSF exposure for PK/PD studies, as well as conduct biomarker analyses. Technical and Study Directors are readily available for consultations, allowing custom study designs to meet your budgetary needs.  

Advantages of in vivo testing with Eurofins:

  • Highly experienced scientific staff - average experience of 15 years
  • Experimental design guided by Technical Director staff with Pharma experience
  • Experience with therapeutics of every type
    • Biologics, vaccines, RNAi, liposomal formulations, nanoparticles, cellular agents or small molecule NCEs.
  • Flexible formulation and dosing options to meet any need
    • Standard methods: ID, IM, IN, IP, IT, IV, PO, SC, topical
    • Short and long term continuous IV infusion
    • Adjustable dose schedule: qd, bid, tid, qid
    • Formulation optimization services available
  • Ancillary services:
    • Clinical chemistry, hematology, blood gases, surgery, bioassay, necropsy, gross pathology, exposure (PK)
  • Consultative, custom model development with wildtype or genetically modified models