JavaScript is disabled. Please enable to continue!
Discovery >> Services >> Efficacy

Efficacy Models

Sidebar Image

Anti-Infectives/Microbiology
undefined
Inflammation/Allergy
undefined
Cardiovascular
undefined
CNS / Pain
undefined
Gastrointestinal/Renal
undefined
Oncology
undefined
Metabolic/Endocrine
undefined
Respiratory
undefined
DMPK
undefined
Safety

Trust the experts at Eurofins with the preclinical assessment of your most promising candidates

The portfolio at Eurofins Pharma Discovery Services provides progressive evaluation of your study from tolerability and exposure through all levels of pharmacodynamics, including primary screening for activity and rank-ordering, lead identification, candidate selection, disease-specific efficacy and dose-dependent proof-of-concept in relevant translational studies.

We provides therapeutically focused disease models, incorporating biomarkers and outcome measures that enable greater prediction of clinical success.  All in vivo studies are supported by a dedicated team of global Technical Directors specializing in specific therapeutic areas.  The scientific experts at Eurofins, with their years of pharmaceutical drug development expertise, provide you ongoing project oversight, with prompt communication and a commitment to on-time reporting, enabling you to meet your strict drug-development timelines.

Our expert laboratory staff can formulate and dose test articles by virtually any route, including short- or long-term continuous infusion, and can monitor blood, brain, tissue and/or CSF exposure for PK/PD studies, as well as conduct biomarker analyses. Technical and Study Directors are readily available for consultations, allowing custom study designs to meet your budgetary needs.  

Advantages of in vivo testing with Eurofins:

  • Highly experienced scientific staff - average experience of 15 years
  • Experimental design guided by Technical Director staff with Pharma experience
  • Experience with therapeutics of every type
    • Biologics, vaccines, RNAi, liposomal formulations, nanoparticles, cellular agents or small molecule NCEs.
  • Flexible formulation and dosing options to meet any need
    • Standard methods: ID, IM, IN, IP, IT, IV, PO, SC, topical
    • Short and long term continuous IV infusion
    • Adjustable dose schedule: qd, bid, tid, qid
    • Formulation optimization services available
  • Ancillary services:
    • Clinical chemistry, hematology, blood gases, surgery, bioassay, necropsy, gross pathology, exposure (PK)
  • Consultative, custom model development with wildtype or genetically modified models