Determine your drug’s similarity to existing drugs with BioPrint®
BioPrint® is a large, homogenous pharmacology and ADME database, which provides a unique resource for supporting the drug discovery decision-making process. The database is composed of three main data sets:
- Chemical descriptors (structures and chemical information, 2D- and 3D- descriptors)
- In vitro data
- Collected and curated in vivo effects of drugs
Our standard BioPrint® profile includes the assays used to explore the properties of >2,500 BioPrint® compounds (consisting of marketed drugs and reference compounds), which establishes individual Pharma-ADME fingerprints for each compound.
BioPrint® positions a new drug candidate in the context of marketed drugs, allowing you to anticipate potential in vivo liabilities, predicting off-target activities, and ADME characteristics (drug profile interpretation). BioPrint® can also help identify secondary therapeutic targets that are not genetically related to a test target (target profile design) for drug repositioning.
Advantages of a BioPrint® profile:
Figure 1. BioPrint® profile heatmap of benzodiazepine receptor interactors