KinaseProfiler and other Screening Solutions
that span the Drug Discovery Process
Join us for this free webinar on October 18, 2016 at 10am EST!
If you are not available at this time please register and we will send you the link to watch the webinar at your convenience.
- Introduction to KinaseProfiler and the importance of profiling
- Profiling beyond the kinome including Ubiquitin E3 ligase cascades, Epigenetic targets, GPCRs, and Ion Channels
- Tailor made protein production and assay development solutions e.g. protein-protein interactions and large scale screening
- Progress your kinase profile into a cellular context with OncoPanel™ Cell-Based Profiling Service
Kinases are one of the most widely-studied and productive drug target classes, with over 20 years in the spotlight for drug discovery research. As members of a family containing over 500 related proteins, profiling candidate compounds for their kinase selectivity is an important aspect of kinase drug development. The competition in this field to find the next breakthrough drug remains high and the requirement for quick assay turn-around and high quality profiling data remains as strong as ever.
Eurofins Pharma Discovery Services brings together a range of services and expertise to rapidly advance the progress of candidate molecules through the drug discovery pipeline. This webinar will highlight the services and other tools available for kinase research, and will include an update on some of the most recent enzyme activity assays developed for the KinaseProfiler™ service at Eurofins. Researchers now have access to a more extensive list of validated kinase assays, including several unique targets, from which customized panels can be designed. Results can be used to assess both compound selectivity and potency. Many of our kinases are available on more than one assay platform, allowing us to support HTS campaigns, lead optimization and preclinical development programs. The presentation will also introduce other key services in the portfolio that support off-target profiling and further characterization of lead compounds.
Meet the Speakers
Anna Woodward, PhD
Anna Woodward manages the Client Services and Project Management team at Eurofins Pharma Discovery Services in Dundee, UK and has been providing general and technical support to users of the KinaseProfiler service for the last 10 years. Prior to joining Eurofins, Anna carried out a 5-year post-doc in biochemistry at the University of Dundee. Anna holds a first degree from the University of Cambridge and a PhD in cell biology from the University of Dundee.
Andrew Plater, PhD
Andrew Plater manages the Assay Development team at Eurofins Pharma Discovery Services in Dundee, UK and has 20 years of assay development expertise on multiple assay platform technologies, including radiometric separation assays, time-resolved fluorescence, ELISA, fluorescence polarization, and ALPHAscreen. Andy has developed over 200 different assays across multiple enzyme classes and on different assay platforms within the biotechnology and drug discovery industries. Prior to joining Eurofins, Andy held Senior Scientist roles at Cyclacel Ltd., Fluorescience and Chiroscience. Andy has obtained a BSc and PhD in Biochemistry from the University of Leeds.